Reduced fronto-striatal white matter integrity in schizophrenia patients and unaffected siblings: a DTI study.
Max de LeeuwMarc M BohlkenRené C W MandlRené S KahnMatthijs VinkPublished in: NPJ schizophrenia (2015)
The result of reduced FA in the tract connecting the left nucleus accumbens and left DLPFC indicates a possible reduction of white matter integrity, commonly associated with schizophrenia. As both patients and unaffected siblings show reduced FA, this may represent a vulnerability factor for schizophrenia.