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Involvement of miR-142 and miR-155 in Non-Infectious Complications of CVID.

Giuliana AmatoFederica VitaPaolina QuattrocchiPaola Lucia MinciulloGiovanni PioggiaSebastiano Gangemi
Published in: Molecules (Basel, Switzerland) (2020)
miR-142 and miR-155 deregulation leads to similar CVID phenotypesin KO mice models. Although no data are available on the involvement of these miRNAs in human CVID, their dysregulation has been detected in human CVID comorbidities. The literature data show that miRNA sequences in murine models are comparable to those in humans; therefore, miR-142 and miR-155 involvement in human CVID could be hypothesized.
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