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Ventrointermediate thalamic stimulation improves motor learning in humans.

Angela VoegtleLaila TerzicAmr FarahatNanna HartongImke GalazkyHermann HinrichsSlawomir J NasutoAdriano de Oliveira AndradeRobert T KnightRichard B IvryJürgen VogesMatthias DelianoLars BuentjenCatherine M Sweeney-Reed
Published in: Communications biology (2024)
Ventrointermediate thalamic stimulation (VIM-DBS) modulates oscillatory activity in a cortical network including primary motor cortex, premotor cortex, and parietal cortex. Here we show that, beyond the beneficial effects of VIM-DBS on motor execution, this form of invasive stimulation facilitates production of sequential finger movements that follow a repeated sequence. These results highlight the role of thalamo-cortical activity in motor learning.
Keyphrases
  • deep brain stimulation
  • functional connectivity
  • high frequency
  • working memory