Combining Machine Learning with a Rule-Based Algorithm to Detect and Identify Related Entities of Documented Adverse Drug Reactions on Hospital Discharge Summaries.

Hui Xing TanChun Hwee Desmond TeoPei San AngWei Ping Celine LokeMun Yee ThamSiew Har TanBee Leng Sally SohPei Qin Belinda FooZheng Jye LingWei Luen James YipYixuan TangJisong YangKum Hoe Anthony TungSreemanee Raaj Dorajoo

Published in: Drug safety (2022)

The proposed hybrid model demonstrates reasonable generalisability on external validation. Rule-based restriction of the detection space results in an approximately 12-14% reduction in recall but improves identification of the related drug and adverse event terms.

Keyphrases

adverse drug
machine learning
drug induced
electronic health record
deep learning
artificial intelligence
big data
loop mediated isothermal amplification
real time pcr
bioinformatics analysis