Glioma hexokinase 3 positively correlates with malignancy and macrophage infiltration.

Tingyu Liang Xingang Zhou Yu Wang Wenbin Ma

Published in: Metabolic brain disease (2024)

This is the first comprehensive research to figure out the relationship between HK3 and TME characteristics in gliomas. HK3 is positively associated with macrophage infiltration and can induce the immunosuppressive TME and malignant phenotype of gliomas.

Keyphrases

high grade
adipose tissue
high glucose
endothelial cells