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Effect of therapeutic-dose heparin on severe acute kidney injury and death in noncritically ill patients hospitalized for COVID-19: a prespecified secondary analysis of the ACTIV4a and ATTACC randomized trial.

Nathaniel R SmilowitzErinn M HadeLucy Z KornblithLana A CastellucciMary CushmanMichael FarkouhMichelle N GongAnna HeathBeverly J HuntKeri S KimAndrei KindzelskiPatrick LawlerDavid E LeafEwan GoligherEric S LeiferBryan J McVerryHarmony R ReynoldsRyan ZarychanskiJudith S HochmanMatthew D NealJeffrey S Berger
Published in: Research and practice in thrombosis and haemostasis (2023)
Therapeutic-dose heparin was associated with a high probability of superiority to reduce the incidence of in-hospital severe AKI or death in patients hospitalized for COVID-19.
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