CCL17 exerts neuroprotection through activation of CCR4/mTORC2 axis in microglia after subarachnoid haemorrhage in rats.

Anke ZhangYibo LiuHoushi XuZeyu ZhangXiaoyu WangLing YuanCameron LenahanChuan ZhangJunkun JiangChaoyou FangYuanjian FangJianmin ZhangSheng Chen

Published in: Stroke and vascular neurology (2022)

CCL17 activated the CCR4/mTORC2 axis in microglia, which can alleviate SAH-induced neurological deficits by promoting M2-like polarisation of microglia.

Keyphrases

inflammatory response
neuropathic pain
liver injury
drug induced
dendritic cells
regulatory t cells
liver fibrosis
traumatic brain injury
high glucose
cerebral ischemia
brain injury
spinal cord
endothelial cells
blood brain barrier
immune response
subarachnoid hemorrhage