Probing different paradigms of morphine withdrawal on sleep behavior in male and female C57BL/6J mice.

Madigan L BedardJulia Sparks LordPatric J PerezIsabel M BravoAdonay T TeklezghiLisa M Tarantino Graham H Diering Zoe A McElligott

Published in: bioRxiv : the preprint server for biology (2022)

Morphine withdrawal differentially dysregulates the sleep of male and female mice3-day precipitated withdrawal results in larger changes than spontaneous withdrawalOpioid withdrawal affects responses to future sleep deprivation differently between sexes.

Keyphrases

sleep quality
physical activity
high fat diet induced
type diabetes
depressive symptoms
single molecule
molecular dynamics simulations
adipose tissue
insulin resistance
skeletal muscle