Circulating tumour cells and hypercoagulability: a lethal relationship in metastatic breast cancer.

Cliona Clare Kirwan T Descamps John Castle

Published in: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico (2019)

The correlation between CTCs, hypercoagulability and reduced survival in MBC suggests the coagulation system supports tumour cell metastasis and is, therefore, a potential therapeutic target.

Keyphrases

metastatic breast cancer
induced apoptosis
cell cycle arrest
single cell
circulating tumor cells
cell therapy
human health
mesenchymal stem cells
risk assessment
pi k akt