Neuropathic-like pain symptoms in inflammatory hand osteoarthritis lower quality of life and may not decrease under prednisolone treatment.
Coen van der MeulenLotte A van de StadtFéline P B KroonMarion C KortekaasAnnelies E R C H BoonenStefan BöhringerMarieke NiestersMonique ReijnierseFrits R RosendaalNaghmeh RiyaziMirian Starmans-KoolFranktien TurkstraJendé van ZebenCornelia F AllaartMargreet KloppenburgPublished in: European journal of pain (London, England) (2022)
Pain is the dominant symptom in hand OA, with an unclear aetiology. In this study, we found that neuropathic-like pain may play a role in hand OA, that it showed associations with female sex, younger age and more comorbidities and that it lowered health-related quality of life in hand OA. Neuropathic-like pain in hand OA seems resistant to prednisolone therapy but did not seem to interfere with the treatment of inflammatory pain with prednisolone.