The importance of considering competing risks in recurrence analysis of intracranial meningioma.
Christian MirianLasse Rehné JensenTareq A JuratliAndrea Daniela MaierSverre H TorpHelen A ShihRamin A MorshedJacob S YoungStephen T MagillLuca BerteroWalter StummerDorothee Cäcilia SpilleBenjamin BrokinkelSoichi OyaSatoru MiyawakiNobuhito SaitoMartin ProescholdtYasuhiro KuroiKonstantinos GousiasMatthias SimonJennifer MoliternoRicardo Prat-AcinStéphane GoutagnyVikram C PrabhuJohn T TsiangJohannes WachErdem GüresirJunkoh YamamotoYoung Zoon KimJoo Ho LeeMatthew KoshyKarthikeyan PerumalMustafa K BaskayaDonald M CannonDennis C ShrieveChang-Ok SuhJong Hee ChangMaria KamenovaSven StraumannJehuda SolemanIlker Y EyüpogluTony CatalanAustin LuiPhilip V TheodosopoulosMichael W McDermottFang WangFuyou GuoPedro GóesManoel Antonio de Paiva NetoAria JamshidiRicardo KomotarMichael IvanEvan LutherLuis SouhamiMarie-Christine GuiotTamás CsonkaToshiki EndoOlivia Claire BarrettRandy JensenTejpal GuptaAkash J PatelTiemo J KlischJun Won KimFrancesco MaiuriValeria BarresiMaria Dolores Tabernero RedondoSimon SkyrmanAnders BroechnerMathias Jacobsen BachIan LawDavid ScheieBjarne Winther KristensenTina Nørgaard MunchTorstein Ragnar MelingKåre FugleholmPaul BlancheTiit MathiesenPublished in: Journal of neuro-oncology (2024)
The importance of considering competing events in recurrence risk analysis is poorly recognized as only 6% of the studies we surveyed employed Aalen-Johansen analyses. Consequently, most of the previous literature has overestimated the risk of recurrence. The overestimation was negligible for studies involving low-grade lesions in younger individuals; however, overestimation might have been substantial for studies on high-grade lesions.