Asparagus cochinchinensis stimulates release of nerve growth factor and abrogates oxidative stress in the Tg2576 model for Alzheimer's disease.
Hyun Ah LeeJi Eun KimJi Eun SungWoo Bin YunDong Seob KimHee Seob LeeJin Tae HongDae Youn HwangPublished in: BMC complementary and alternative medicine (2018)
These results suggest that AEAC contribute to improving the deposition of Aβ-42 peptides and neuronal cell injuries during the pathological progression stage of AD in the brain of Tg2576 mice through increased NGF secretion and suppressed oxidative stress.
Keyphrases
- growth factor
- oxidative stress
- dna damage
- ischemia reperfusion injury
- diabetic rats
- single cell
- induced apoptosis
- cerebral ischemia
- cell therapy
- white matter
- cognitive decline
- high fat diet induced
- type diabetes
- metabolic syndrome
- skeletal muscle
- peripheral nerve
- subarachnoid hemorrhage
- signaling pathway
- mesenchymal stem cells
- endoplasmic reticulum stress