Exosomes derived from stem cells from apical papilla promote craniofacial soft tissue regeneration by enhancing Cdc42-mediated vascularization.

Yao LiuXueying ZhuangSi YuNing YangJianhong ZengXuemei LiuXu Chen

Published in: Stem cell research & therapy (2021)

This study demonstrated that SCAP-Exo had a superior effect on angiogenesis and effectively promoted craniofacial soft tissue regeneration. These data provide a new option for SCAP-Exo to be used in a cell-free approach to optimize tissue regeneration in the clinic.

Keyphrases

stem cells
soft tissue
cell free
cell therapy
endothelial cells
wound healing
electronic health record
cell cycle
vascular endothelial growth factor
machine learning
big data
bone marrow
deep learning
cell proliferation