Impact of Early Diabetic Ketoacidosis on the Developing Brain.
Michael TanseyPaul K MazaikaNelly MaurasMatthew J MarzelliHanyang ShenTamara HersheyAllison CatoStuart A WeinzimerNeil H WhiteEva TsalikianBooil JoAllan L Reissnull nullPublished in: Diabetes care (2018)
A single episode of moderate/severe DKA in young children at diagnosis is associated with lower cognitive scores and altered brain growth. Further studies are needed to assess whether earlier diagnosis of type 1 diabetes and prevention of DKA may reduce the long-term effect of ketoacidosis on the developing brain.