Diversification of Orientia tsutsugamushi genotypes by intragenic recombination and their potential expansion in endemic areas.

Gwanghun KimNa-Young HaChan-Ki MinHong-Il KimNguyen Thi Hai YenKeun-Hwa LeeInbo OhJae-Seung KangMyung-Sik ChoiIk-Sang KimNam-Hyuk Cho

Published in: PLoS neglected tropical diseases (2017)

Fluctuation and diversification of vector species harboring O. tsutsugamushi in local endemic areas may facilitate genetic recombination among diverse genotypes. Therefore, careful monitoring of dominant vector species, as well as the prevalence of O. tsutsugamushi genotypes may be advisable to enable proper anticipation of epidemiological changes of scrub typhus.

Keyphrases

dna damage
dna repair
risk factors
genetic diversity
copy number
gene expression
oxidative stress