Cardiovascular protective effects of PPARγ agonists in hypothyroid rats: protection against oxidative stress.

Yousef BaghcheghiFarimah BeheshtiMahmoud HosseiniArezoo Gowhari-ShabgahMohammad Ali-HassanzadehMahdiyeh Hedayati-Moghadam

Published in: Clinical and experimental hypertension (New York, N.Y. : 1993) (2022)

The results of this study showed that administration of POG or RSG decreased oxidative damage in the heart and aorta tissues induced by hypothyroidism in rats.

Keyphrases

oxidative stress
heart failure
gene expression
dna damage
aortic valve
insulin resistance
atrial fibrillation
skeletal muscle
replacement therapy
diabetic rats
adipose tissue
signaling pathway
induced apoptosis
pulmonary hypertension