Mathematical modeling of pneumococcal transmission dynamics in response to PCV13 infant vaccination in Germany predicts increasing IPD burden due to serotypes included in next-generation PCVs.

Matthias HornChristian TheilackerRalf SprengerChristof von EiffErnestine MaharJulia Schiffner-RoheMathias W PletzMark van der LindenMarkus Scholz

Published in: PloS one (2023)

We conclude that introduction of next-generation PCVs for adults may prevent a substantial and increasing proportion of adult IPDs, with PCV20 having the potential to provide the broadest protection against pneumococcal disease.

Keyphrases

risk factors
human health
risk assessment
young adults
childhood cancer