Frontal Behavior Syndromes in Idiopathic Normal Pressure Hydrocephalus as a Function of Alzheimer's Disease Biomarker Status.
Madison NiermeyerChad GaudetPaul MalloyIrene PiryatinskyStephen SallowayPetra KlingeAthene LeePublished in: Journal of the International Neuropsychological Society : JINS (2020)
These results replicate and extend prior research by identifying apathy and executive dysfunction as prominent neuropsychiatric symptoms of iNPH and suggest comorbid AD exacerbates dysexecutive behaviors. Future research is warranted to examine the effects of comorbid AD pathology in response to shunt surgery for iNPH, neuropsychiatric symptom changes, and resultant caregiver burden.
Keyphrases
- working memory
- minimally invasive
- coronary artery bypass
- subarachnoid hemorrhage
- current status
- cognitive decline
- oxidative stress
- pulmonary artery
- cerebrospinal fluid
- functional connectivity
- risk factors
- sleep quality
- brain injury
- acute coronary syndrome
- depressive symptoms
- mild cognitive impairment
- physical activity
- percutaneous coronary intervention