Yield of Gluten Challenge in Patients on Self-Prescribed Gluten-Free Diets.
Martin VentosoJohn Henry IgnatievSeokyu ShinSuneeta KrishnareddySuzanne LewisPeter H R GreenBenjamin LebwohlPublished in: Digestive diseases and sciences (2024)
Among patients undergoing GC for diagnostic purposes, only 14% had evidence of villus atrophy corresponding with CD on duodenal biopsy. The presence of any elevated pre-challenge serology was associated with CD. Bloating in combination with low serologies may help risk stratify patients as being less likely to have CD upon GC.