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Exploratory toxicology studies of 2,3-substituted imidazo[1,2- a ]pyridines with antiparasitic and anti-inflammatory properties.

Jose Ivan Serrano ContrerasMaría Estela Meléndez-CamargoYazmín Karina Márquez-FloresMartha Patricia Soria-SerranoMaría-Elena Campos Aldrete
Published in: Toxicology research (2022)
These compounds can continue non-clinical evaluations, and if possible, clinical trials as new candidates to treat trichomoniasis and amoebiasis, and inflammatory diseases. Further studies are also needed to fully elucidate a proposed dual effect that may exert these molecules against trichomoniasis and amoebiasis, which may also signify a novel mechanism of action to treat these infections.
Keyphrases
  • clinical trial
  • anti inflammatory
  • case control
  • molecular docking
  • phase ii
  • study protocol
  • molecular dynamics simulations