Exploratory toxicology studies of 2,3-substituted imidazo[1,2- a ]pyridines with antiparasitic and anti-inflammatory properties.
Jose Ivan Serrano ContrerasMaría Estela Meléndez-CamargoYazmín Karina Márquez-FloresMartha Patricia Soria-SerranoMaría-Elena Campos AldretePublished in: Toxicology research (2022)
These compounds can continue non-clinical evaluations, and if possible, clinical trials as new candidates to treat trichomoniasis and amoebiasis, and inflammatory diseases. Further studies are also needed to fully elucidate a proposed dual effect that may exert these molecules against trichomoniasis and amoebiasis, which may also signify a novel mechanism of action to treat these infections.