Coexistence of anti-MDA5 and anti-PL-7 in a patient with dermatomyositis: A case report.
Hongyan FuShaofeng SunHong ZhangShuhong ChiWeirong MaGuilan YangJuan ChenPublished in: Clinical case reports (2023)
Coexisting anti-MDA5 and anti-PL-7 antibodies are extremely rare. Anti-MDA5 is associated with rapidly progressive interstitial lung disease (RP-ILD), while anti-PL-7 is often associated with chronic or subacute ILD and better outcomes than RP-ILD. We report a 41-year-old woman diagnosed with dermatomyositis (DM)-associated ILD positive for anti-MDA5 and anti-PL-7.