Mendelian Randomization Study of Obesity and Cerebrovascular Disease.

Sandro MariniJordi MerinoBailey E MontgomeryRainer MalikCatherine L SudlowMartin DichgansJose C FlorezJonathan RosandDipender GillChristopher D Andersonnull null

Published in: Annals of neurology (2020)

Abdominal adiposity may trigger causal pathological processes, partially independent from blood pressure and totally independent from glucose levels, that lead to cerebrovascular disease. Potential targets of these pathological processes could represent novel therapeutic opportunities for stroke. ANN NEUROL 2020;87:516-524.

Keyphrases

blood pressure
insulin resistance
type diabetes
weight gain
atrial fibrillation
weight loss
heart rate
adipose tissue
hypertensive patients
risk assessment
skeletal muscle
physical activity
climate change
subarachnoid hemorrhage