The role of TaqI, ApaI and BsmI polymorphisms of VDR gene in lumbar spine pathologies: systematic review and meta-analysis.

Rosa Giannina Castillo-AvilaThelma Beatriz González-CastroCarlos Alfonso Tovilla-ZárateIsela Esther Juárez-RojopMaría Lilia López-NarváezJosé Manuel Rodríguez-PérezNonanzit Pérez-Hernández

Published in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2021)

Our findings indicate that TaqI and ApaI polymorphisms of the VDR gene are important risk factors for developing lumbar spine pathologies. Moreover, the TaqI polymorphism is a risk factor for lumbar disc degeneration.

Keyphrases

copy number
genome wide
genome wide identification
minimally invasive
gene expression
dna methylation