Analgesic effects of the CTK 01512-2 toxin in different models of orofacial pain in rats.

Emanuelle Sistherenn CaminskiLeandro Mendes de FreitasEliane DallegraveClaudio Antônio da Silva JuniorMarcus Vinicius GomezElizete Maria Rita PereiraFlávia Tasmim Techera AntunesAlessandra Hubner de Souza

Published in: Pharmacological reports : PR (2020)

The roles of TRPA1 in pain transduction and the performance of CTK 01512-2 in the inhibition of the N-type VGCCs were reinforced. This dual activity may represent an advantage in clinical treatments.

Keyphrases

neuropathic pain
chronic pain
pain management
escherichia coli
spinal cord
spinal cord injury
postoperative pain