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Busulfan and subsequent malignancy: An evidence-based risk assessment.

Janel R Long-BoyleDonald B KohnAmi J ShahSueli Marques SpencerJulian SevillaClaire BoothJosé Luis López LorenzoEileen NicolettiArpita ShahMeredith ReatzJoana MatosJonathan D Schwartz
Published in: Pediatric blood & cancer (2023)
The incidence of busulfan-related secondary malignancies is low, and likely to be substantially less than 1% in pediatric transplant recipients, especially those receiving busulfan monotherapy for nonmalignant conditions other than SCD.
Keyphrases
  • risk assessment
  • allogeneic hematopoietic stem cell transplantation
  • risk factors
  • human health
  • combination therapy
  • open label
  • clinical trial
  • acute myeloid leukemia
  • young adults
  • childhood cancer