Hip Fracture Risk in Antiepileptic Drug Initiators and Non-Initiators with Alzheimer's Disease.

Federica PisaJonas Reinold Piia LavikainenMarjaana KoponenHeidi Taipale Antti Tanskanen Jari TiihonenSirpa HartikainenAnna-Maija Tolppanen

Published in: Clinical epidemiology (2021)

Our results imply that AED use is associated with an increased risk of hip fracture in people with AD. These findings prompt careful consideration before prescribing AEDs to persons with AD. Persons with AD treated with antiepileptics should be carefully monitored due to their increased risk of falling and fractures.

Keyphrases

hip fracture
primary care
adverse drug
cognitive decline
emergency department
newly diagnosed
mild cognitive impairment