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Medications on hypertension, hyperlipidemia, diabetes, and risk of amyotrophic lateral sclerosis: a systematic review and meta-analysis.

Nan HuHongyan Ji
Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2022)
Regular use of anti-hypertensive drugs and anti-diabetes including ACEIs, beta-blockers, CCBs, diuretics, metformin, and sulfonylureas could protect against the incidence of ALS. No significant association between anti-hyperlipidemia drug use and risk of ALS was revealed. Regular medications for hypertension, hyperlipidemia, and diabetes should be recommended regardless of the diagnosis of ALS.
Keyphrases
  • amyotrophic lateral sclerosis
  • blood pressure
  • type diabetes
  • cardiovascular disease
  • glycemic control
  • high fat diet
  • single cell
  • high fat diet induced
  • metabolic syndrome
  • angiotensin ii