The relevance of CT-based geometric and radiomics analysis of whole liver tumor burden to predict survival of patients with metastatic colorectal cancer.
Alexander MühlbergJulian W HolchVolker HeinemannThomas HuberJan MoltzStefan MaurusNils JägerLian LiuMatthias F FroelichAlexander KatzmannEva GresserOliver TaubmannMichael SühlingDominik NörenbergPublished in: European radiology (2020)
• CT-based geometric distribution and radiomics analysis of whole liver tumor burden in metastatic colorectal cancer patients yield prognostic information. • Differences in survival are possibly attributable to the spatial distribution of metastatic lesions and the geometric metastatic spread analysis of all liver metastases may serve as robust imaging biomarker invariant to technical variation. • Imaging-based prediction models outperform clinical models for 1-year survival prediction in metastatic colorectal cancer patients with liver metastases.
Keyphrases
- metastatic colorectal cancer
- liver metastases
- contrast enhanced
- squamous cell carcinoma
- high resolution
- small cell lung cancer
- computed tomography
- end stage renal disease
- free survival
- image quality
- newly diagnosed
- lymph node metastasis
- ejection fraction
- dual energy
- chronic kidney disease
- magnetic resonance imaging
- prognostic factors
- positron emission tomography
- magnetic resonance
- risk factors
- healthcare
- fluorescence imaging
- patient reported outcomes
- patient reported
- social media