Germline TP53 mutation spectrum in Sudanese premenopausal breast cancer patients: correlations with reproductive factors.

Gitana Maria AcetoKhalid Dafaallah AwadelkarimMarta Di NicolaCarmelo MoscatelloMattia Russel PantaloneFabio VerginelliNasr Eldin ElwaliRenato Mariani-Costantini

Published in: Breast cancer research and treatment (2019)

Our study suggests that the codon 72 Arg>Pro polymorphism is not implicated in premenopausal BC susceptibility, whereas multiparity and breastfeeding might be BC risk factors for carriers of deleterious TP53 mutations.

Keyphrases

postmenopausal women
preterm infants
dna repair
anti inflammatory
breast cancer risk