Improvement of β-Cell Function After Switching From DPP-4 Inhibitors to Oral Semaglutide: SWITCH-SEMA2 Post Hoc Analysis.

Hiroshi NomotoSho FurusawaHiroki YokoyamaYuka SuzukiRimi IzumiharaYuki OeKiyohiko TakahashiAika MiyaHiraku KamedaKyu Yong ChoJun TakeuchiYoshio KuriharaAkinobu NakamuraTatsuya Atsumi

Published in: The Journal of clinical endocrinology and metabolism (2024)

Switching to oral semaglutide ameliorated β-cell function compared with DPP-4is, presumably via tissue-to-tissue crosstalk between liver and β-cells.

Keyphrases

induced apoptosis
cell cycle arrest
oxidative stress
cell death
cell proliferation