Nucleic acid oxidation is associated with biomarkers of neurodegeneration in CSF in people with HIV.
Ronald J EllisDavid J MooreErin E SundermannRobert K HeatonSanjay MehtaTodd HulganDavid SamuelsJerel A FieldsScott L LetendrePublished in: Neurology(R) neuroimmunology & neuroinflammation (2020)
This study provides Class II evidence that among virologically suppressed PWH, nucleic acid oxidation is associated with standard CSF biomarkers of neurodegeneration.