IgE autoantibodies in serum and skin of non-bullous and bullous pemphigoid patients.
A LambertsN KotnikGilles F H DiercksJoost M MeijerGiovanni Di ZenzoHendri H PasM F JonkmanBernhard F GibbsUlrike RaapBarbara HorváthPublished in: Journal of the European Academy of Dermatology and Venereology : JEADV (2020)
Since IgE was present in the serum and skin of both NBP and BP patients, this supports IgE-dependent mechanisms common to both diseases, such as pruritus. However, it remains to be elucidated whether IgE contributes to blister formation in BP.