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Targeting neuro-immune communication in neurodegeneration: Challenges and opportunities.

Aleksandra DeczkowskaMichal Schwartz
Published in: The Journal of experimental medicine (2018)
Immune cells patrol the brain and can support its function, but can we modulate brain-immune communication to fight neurological diseases? Here, we briefly discuss the mechanisms orchestrating the cross-talk between the brain and the immune system and describe how targeting this interaction in a well-controlled manner could be developed as a universal therapeutic approach to treat neurodegeneration.
Keyphrases
  • resting state
  • white matter
  • cerebral ischemia
  • functional connectivity
  • cancer therapy
  • blood brain barrier