Targeting neuro-immune communication in neurodegeneration: Challenges and opportunities.
Aleksandra DeczkowskaMichal SchwartzPublished in: The Journal of experimental medicine (2018)
Immune cells patrol the brain and can support its function, but can we modulate brain-immune communication to fight neurological diseases? Here, we briefly discuss the mechanisms orchestrating the cross-talk between the brain and the immune system and describe how targeting this interaction in a well-controlled manner could be developed as a universal therapeutic approach to treat neurodegeneration.