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Leber's Hereditary Optic Neuropathy with Mitochondrial DNA Mutation G11778A: A Systematic Literature Review and Meta-Analysis.

Jiajia YuanJiaxun ZhaoChong YeLong PangXin ZhangAlvin LukYangyang DuKai Yoon FanXiaowen ZhangBin LiChangzheng Chen
Published in: BioMed research international (2023)
The G11778A mutation is a prevalent mitochondrial DNA mutation accounting for over half of LHON cases with three primary mutations. Spontaneous visual recovery is rare, and no effective treatment is currently available.
Keyphrases
  • mitochondrial dna
  • copy number
  • genome wide
  • gene expression