Highly activated p53 contributes to selectively increased apoptosis of latently HIV-1 infected cells upon treatment of anticancer drugs.

YoungHyun ShinHoyong LimByeong-Sun ChoiKyung-Chang KimChun KangYong-Soo BaeCheol-Hee Yoon

Published in: Virology journal (2016)

Evidence described here indicate that when treated with anticancer drugs, apoptosis of cells with latent HIV-1 infection was increased via the p53 activation pathway and may provide information for application of anticancer drugs to selectively eliminate HIV-1 reservoirs.

Keyphrases

cell cycle arrest
hiv infected
induced apoptosis
antiretroviral therapy
cell death
endoplasmic reticulum stress
pi k akt
oxidative stress
signaling pathway
hiv aids
healthcare
hepatitis c virus
cell proliferation
social media
newly diagnosed