Lifetime cocaine use is a potential predictor for conversion from major depressive disorder to bipolar disorder: A prospective study.

Taiane de Azevedo CardosoKaren JansenThaise C MondinFernanda Pedrotti MoreiraSuelen de Lima BachRicardo Azevedo da SilvaLuciano D de Mattos SouzaVicent Balanzá-MartínezBenicio N FreyFlavio Kapczinski

Published in: Psychiatry and clinical neurosciences (2020)

These findings showed that lifetime cocaine use is a potential predictor of conversion to BD in an MDD cohort. Further studies are needed to assess the possible underlying mechanisms linking exposure to cocaine with BD conversion.

Keyphrases

major depressive disorder
bipolar disorder
prefrontal cortex
human health
risk assessment