Two new compounds from Pergularia tomentosa growing wildly in Jordan.

Phytochemical investigation of the aerial parts and latex of Pergularia tomentosa from Jordan, utilizing column chromatography accompanied with NMR (1 & 2D), IR, UV, and HR-ESI-Mass spectroscopy have led to the isolation and characterization of two new compounds, pergularol (1) and 3-O-acetyl-28-hydroxytaraxasterol (2) for the first time along with other ten known compounds including linoleic acid (3) , 3'-didehydroafroside (4) , apigenin (5) , β-sitosteryl glucoside (6) , luteolin (7) , apigenin 7-(6''-crotonoyl)glucoside (8) , 3'-O-β-glucopyranosylcalotropin (9) , apigenin-7-O-β-D-glycoside (10) , pergularine A (11) , taraxasterol (12) . Compound (8) is isolated for the first time from Pergularia genus.