Comparison of Efficacy and Safety of First-Line Treatment Options for Unresectable Stage III Non-Small Cell Lung Cancer: A Retrospective Analysis.
Luqing ZhaoZhiting ZhaoXiaoqi YanFei WuNing SunRenhong GuoShaorong YuXiao HuJi-Feng FengPublished in: International journal of clinical practice (2024)
For unresectable stage III NSCLC patients with wild-type driver genes, the combination of radiotherapy and immunotherapy in the initial treatment was essential to significantly improve the efficacy. For patients with mutant driver genes, radiotherapy, targeted therapy, and the combination of radiotherapy and targeted therapy showed similar short-term efficacy.
Keyphrases
- locally advanced
- wild type
- early stage
- rectal cancer
- radiation therapy
- squamous cell carcinoma
- radiation induced
- genome wide
- small cell lung cancer
- genome wide identification
- liver metastases
- bioinformatics analysis
- advanced non small cell lung cancer
- dna methylation
- transcription factor
- gene expression
- combination therapy