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Craniometric Analysis of the Hindbrain and Craniocervical Junction of Chihuahua, Affenpinscher and Cavalier King Charles Spaniel Dogs With and Without Syringomyelia Secondary to Chiari-Like Malformation.

Susan Penelope KnowlerAnna-Mariam KivirantaAngus K McFadyenTarja S JokinenRoberto M La RagioneClare Rusbridge
Published in: PloS one (2017)
The selected morphometries successfully characterised conformational changes in the brain and craniocervical junction that might form the basis of a diagnostic tool for all breeds. The severity of SM involved a spectrum of abnormalities, incurred by changes in both angulation and size that could alter neural parenchyma compliance and/or impede cerebrospinal fluid channels.
Keyphrases
  • cerebrospinal fluid
  • molecular dynamics
  • resting state
  • molecular dynamics simulations
  • white matter
  • single molecule
  • functional connectivity
  • genetic diversity