Assessment of perfusion deficit with early phases of [ 18 F]PI-2620 tau-PET versus [ 18 F]flutemetamol-amyloid-PET recordings.
Friederike VölterLeonie BeyerFlorian EckenweberMaximilian ScheifeleNgoc BuiMarianne PattHenryk BarthelSabrina KatzdoblerCarla PalleisNicolai FranzmeierJohannes LevinRobert PerneczkyBoris-Stephan RauchmannOsama SabriJimin HongPaul CummingAxel RomingerKuangyu ShiPeter BartensteinMatthias BrendelPublished in: European journal of nuclear medicine and molecular imaging (2022)
F]flutemetamol-amyloid-PET are roughly equivalent indices of perfusion defect indicative of regional and lobar neuronal injury in patients with various neurodegenerative diseases. As such, either tracer may serve for two diagnostic channels by assessment of amyloid/tau status and neuronal activity.