Maternal blood-pressure trends throughout pregnancy and development of pre-eclampsia in women receiving first-trimester aspirin prophylaxis.
Ahmet Alexander BaschatD DewberryViola SeravalliJena L MillerD Block-AbrahamM G BlitzerPublished in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2018)
In women treated with prophylactic aspirin from the first trimester, those who develop pre-eclampsia have significantly and sustained higher blood pressure from the onset of pregnancy compared with those who do not develop pre-eclampsia. This raises the possibility that mildly elevated blood pressure predisposes women to abnormal placentation, which then acts synergistically with elevated blood pressure to predispose such women to pre-eclampsia to a degree that is incompletely mitigated by aspirin. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd.
Keyphrases
- blood pressure
- pregnancy outcomes
- polycystic ovary syndrome
- low dose
- hypertensive patients
- heart rate
- pregnant women
- cardiovascular events
- cervical cancer screening
- breast cancer risk
- blood glucose
- body mass index
- adipose tissue
- insulin resistance
- type diabetes
- cardiovascular disease
- skeletal muscle
- coronary artery disease