Biomarkers of hypoxic-ischemic encephalopathy: a systematic review.

Inês CarameloMargarida CoelhoMiguel RosadoCarla M P CardosoAlexandra DinisCarlos B DuarteMário GrãosBruno Manadas

Published in: World journal of pediatrics : WJP (2023)

Neuron-specific enolase and S100-calcium-binding protein-B are potential biomarkers, since they are correlated with an unfavorable outcome of hypoxic-ischemic encephalopathy newborns. However, more studies are required to determine the sensitivity and specificity of this approach to be validated for clinical practice.

Keyphrases

binding protein
clinical practice
early onset
pregnant women
gestational age
cord blood
low birth weight
preterm infants
structural basis
preterm birth