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The complex syndrome of functional neurological disorder.

Zuzana ForejtováTereza SerranováTomas SiegerMatěj SlovákLucia NovákováGabriela VěchetováEvžen RůžičkaMark John Edwards
Published in: Psychological medicine (2022)
We interpret the lack of evidence of clusters along with a high degree of correlation between all self-reported and objective measures of motor or non-motor symptoms and HRQoL within current neurobiological models as evidence to support a unified pathophysiology of 'functional' symptoms. Our results support the unification of functional and somatic syndromes in classification schemes and for future mechanistic and therapeutic research.
Keyphrases
  • deep learning
  • gene expression
  • depressive symptoms
  • physical activity