The complex syndrome of functional neurological disorder.
Zuzana ForejtováTereza SerranováTomas SiegerMatěj SlovákLucia NovákováGabriela VěchetováEvžen RůžičkaMark John EdwardsPublished in: Psychological medicine (2022)
We interpret the lack of evidence of clusters along with a high degree of correlation between all self-reported and objective measures of motor or non-motor symptoms and HRQoL within current neurobiological models as evidence to support a unified pathophysiology of 'functional' symptoms. Our results support the unification of functional and somatic syndromes in classification schemes and for future mechanistic and therapeutic research.