Elexacaftor-Tezacaftor-Ivacaftor corrects monocyte microbicidal deficiency in cystic fibrosis.

Luca CavinatoFrancesco R LulyValentina PastoreDaniele ChiappettaGloria SangiorgiEva FerraraPia BaiocchiGiuseppe MandarelloGiuseppe CiminoPaola Del PortoFiorentina Ascenzioni

Published in: The European respiratory journal (2022)

, which may have contributed to the overall effect of ETI on pulmonary disease. This also suggests that CF monocyte dysfunctions may be specifically targeted to ameliorate lung function in CF.

Keyphrases

cystic fibrosis
lung function
dendritic cells
pseudomonas aeruginosa
endothelial cells
peripheral blood
pulmonary hypertension
cancer therapy
immune response
replacement therapy
smoking cessation