Validation of a perioperative population factor VIII pharmacokinetic model with a large cohort of pediatric hemophilia a patients.

Tim PreijersRi LiesnerHendrika C A M HazendonkPratima ChowdaryMariëtte H E DriessensDan P HartBritta A P Laros-van GorkomFelix J M van der MeerKarina MeijerKarin FijnvandraatFrank W G LeebeekRon A A MathôtMarjon H Cnossennull null

Published in: British journal of clinical pharmacology (2021)

This study emphasizes the importance of external validation of population PK models using real-life data.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
patients undergoing
peritoneal dialysis
electronic health record
cardiac surgery
big data
patient reported outcomes
machine learning
young adults
deep learning