Paraoxonase 1 (PON1) promoter (-107T/C) and coding region (192Q/R and 55L/M) genetic variations in pseudoexfoliation syndrome and pseudoexfoliative glaucoma risk.

Birsen Can DemirdöğenCanan Koçan AkçinEzgi GöksoyGizem YakarTuğçe ÖztepeSinem Demirkaya-BudakSinan Oflaz

Published in: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (2019)

This study, for the first time, analyzed the relationship between PON1 genetic variants, clinical visual parameters, and PEX/PEG. The results indicated a possible role for the PON1 promoter variant in PEX.

Keyphrases

dna methylation
transcription factor
gene expression
genome wide
drug delivery
copy number
optical coherence tomography