Single-cell transcriptomics reveals immune reconstitution in R/R T-ALL/LBL patients with donor-derived CD7 CAR-T therapy.

Wei Chen Hui Shi Zhuojun Liu Fan Yang Jia Liu Leqiang Zhang Yajin Wu Yuanshi Xia Yuxuan Ou Ruiting Li Ting Zhang Jiecheng Zhang Xiaoyan Ke Kai Hu Jian Yu

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)

Our data revealed cellular level dynamics of immune homeostasis of CD7 CAR-T therapy, which is valuable for optimizing the treatment of R/R T-ALL/LBL.

Keyphrases

single cell
rna seq
high throughput
electronic health record
stem cells
mesenchymal stem cells
deep learning
cell therapy
combination therapy