Clinical-grade N-(4-[18F]fluorobenzoyl)-interleukin-2 for PET imaging of activated T-cells in humans.
Elly L van der VeenInês F AntunesPetra MaarsinghJanet Hessels-ScheperRolf ZijlmaHendrikus H BoersmaAnnelies Jorritsma-SmitGeke A P HospersElisabeth G E de VriesMarjolijn N Lub-de HoogeErik F J de VriesPublished in: EJNMMI radiopharmacy and chemistry (2019)
To enable the use of [18F]FB-IL2 in clinical studies, a fully automated GMP compliant production process was developed. [18F]FB-IL2 is now produced consistently for use in clinical studies.