Metabolomic Analysis of Human Cirrhosis and Hepatocellular Carcinoma: A Pilot Study.
Sabine WeberKristian UngerMarianna Alunni-FabbroniHeidrun Hirner-EppenederElif ÖcalHorst ZitzelsbergerJulia MayerlePeter MalfertheinerJens RickePublished in: Digestive diseases and sciences (2024)
Our findings give promising insides into the metabolic changes during HCC carcinogenesis and provide candidate biomarkers for future studies. Campesterol and furoylglycine in particular were identified as possible biomarkers for HCC progression. Moreover, eight metabolites were detected as predictors for poor overall survival.