Biliary microbial patterns in primary sclerosing cholangitis are linked to poorer transplant-free survival.
Burcin ÖzdirikMaria ScherfAna BrumercekJule M NicklausTassilo KruisPhilipp K HaberJohann PratschkeFrank TackeMichael SigalPublished in: Hepatology communications (2023)
Our data indicate that in patients with PSC, presence of Enterococcus spp. and Candida spp. in bile is associated with an adverse outcome. Concomitant IBD is linked to presence of microbes in bile, and proton pump inhibitor intake is a feature associated with biliary candidiasis in patients with PSC.
Keyphrases
- free survival
- candida albicans
- biofilm formation
- ulcerative colitis
- microbial community
- machine learning
- electronic health record
- deep learning
- pseudomonas aeruginosa
- big data
- emergency department
- staphylococcus aureus
- body mass index
- escherichia coli
- cystic fibrosis
- artificial intelligence
- weight gain
- weight loss
- drug induced